Anti-SWAP70 Polyclonal Antibody
Cat: K110239P
Summary:
| 【Product name】：Anti-SWAP70 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：23075 | 【Swiss Prot】：Q9UH65 |
| 【Tested applications】：IF,IHC,WB | |
| 【Recommended dilution】：WB 1:8000-12000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human SWAP70 | |
| 【Public Immunogen Range】：20-70/585aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
Verified picture:
Western blot analysis with SWAP70 antibody diluted at 1:8000;Lane:Raji,Raw264.7
Immunohistochemistry of paraffin-embedded Human tonsil using SWAP70 antibody diluted at 1:80