Anti-GCSAM Polyclonal Antibody - Biotin
Cat: K110255P - Biotin
Summary:
| 【Product name】：Anti-GCSAM Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：257144 | 【Swiss Prot】：Q8N6F7 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human GCSAM | |
| 【Public Immunogen Range】：128-178/178aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
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