Anti-DYRK1B Polyclonal Antibody - SAlexa Fluor 647
Cat: K110261P - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-DYRK1B Polyclonal Antibody - SAlexa Fluor 647 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9149 | 【Swiss Prot】：Q9Y463 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human DYRK1B | |
| 【Public Immunogen Range】：245-295/629aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
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