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Anti-DYRK1B Polyclonal Antibody - SAlexa Fluor 594
Cat: K110262P - SAlexa Fluor 594
Summary:
【Product name】:Anti-DYRK1B Polyclonal Antibody - SAlexa Fluor 594 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:9149 【Swiss Prot】:Q9Y463
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human DYRK1B
【Public Immunogen Range】:245-295/629aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
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