Anti-USP49 Polyclonal Antibody
Cat: K110263P
Summary:
| 【Product name】：Anti-USP49 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：25862 | 【Swiss Prot】：Q70CQ1 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human USP49 | |
| 【Public Immunogen Range】：365-415/688aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer using USP49 antibody diluted at 1:200