Anti-BDKRB1 Polyclonal Antibody - SAlexa Fluor 594
Cat: K110276P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-BDKRB1 Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：623 | 【Swiss Prot】：P46663 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human BDKRB1 | |
| 【Public Immunogen Range】：190-240/353aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
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