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Anti-YWHAE Polyclonal Antibody - SAlexa Fluor 594
Cat: K110297P - SAlexa Fluor 594
Summary:
【Product name】:Anti-YWHAE Polyclonal Antibody - SAlexa Fluor 594 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:7531 【Swiss Prot】:P62258
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human YWHAE
【Public Immunogen Range】:35-85/255aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
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