Anti-ARFGAP1 Polyclonal Antibody
Cat: K110312P
Summary:
| 【Product name】：Anti-ARFGAP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：55738 | 【Swiss Prot】：Q8N6T3 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human ARFGAP1 | |
| 【Public Immunogen Range】：115-165/406aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with ARFGAP1 antibody diluted at 1:2000;Lane:Rat brain,MCF7,HepG2,Hela,C2C12
Immunohistochemistry of paraffin-embedded Human colorectal cancer using ARFGAP1 antibody diluted at 1:100