Anti-DBF4B Polyclonal Antibody
Cat: K110385P
Summary:
| 【Product name】：Anti-DBF4B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：80174 | 【Swiss Prot】：Q8NFT6 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human DBF4B | |
| 【Public Immunogen Range】：81-432aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle.
Verified picture:
Western blot analysis with DBF4B antibody diluted at 1:2000;Lane:MCF7,A549,SHSY5Y,U937,THP-1