Anti-IL18 Polyclonal Antibody
Cat: K110408P
Summary:
| 【Product name】：Anti-IL18 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3606 | 【Swiss Prot】：Q14116 |
| 【Tested applications】：WB;IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IL18 | |
| 【Public Immunogen Range】：1-193aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable).
Verified picture:
Western blot analysis with IL18 antibody diluted at 1:2000;Lane:A431,PC-3M-IE8,HeLa
Immunohistochemistry of paraffin-embedded Human thyroid cancer using IL18 antibody diluted at 1:100