Anti-AAK1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K009899P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-AAK1 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity Purification |
| 【Gene ID】：22848 | 【Swiss Prot】：Q2M2I8 |
| 【Tested applications】：WB,IHC,ELISA | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-50. ELISA 1:5000-10000. | |
| 【Immunogen】：Recombinant protein of human AAK1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
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