Anti-LXN Polyclonal Antibody
Cat: K009903P
Summary:
| 【Product name】：Anti-LXN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity Purification |
| 【Gene ID】：56925 | 【Swiss Prot】：Q9BS40 |
| 【Tested applications】：WB,ELISA,IHC | |
| 【Recommended dilution】：WB 1:1000-5000. IHC 1:25-100. ELISA 1:2000-10000. | |
| 【Immunogen】：Recombinant protein of human LXN | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Latexin, also designated endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), belongs to the protease inhibitor I47 family of proteins. Latexin acts as a non-competitive, reversible inhibitor for metallocarboxypeptidases (MCPs), including CPA1, CPA2 and CPA4. It is a cytoplasmic protein that is highly expressed in heart, prostate, pancreas, ovary, kidney, brain and colon. Latexin consists of two topologically equivalent subdomains that bind to MCPs with low specificity, which gives it with the flexibility to inhibit all vertebrate A/B MCPs.
Verified picture:
Western blot analysis with LXN antibody diluted at 1:667;Lane:A549
Immunohistochemistry of paraffin-embedded Human cervical cancer using LXN antibody diluted at 1:25