Anti-PLOD3 Polyclonal Antibody - SAlexa Fluor 405
Cat: K009875P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-PLOD3 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity Purification |
| 【Gene ID】：8985 | 【Swiss Prot】：O60568 |
| 【Tested applications】：IHC,ELISA,WB | |
| 【Recommended dilution】：WB 1:1000-5000. IHC 1:50-100. ELISA 1:5000-10000. | |
| 【Immunogen】：Recombinant protein of human PLOD3 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
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