Anti-RBL2 Polyclonal Antibody
Cat: K009881P
Summary:
| 【Product name】：Anti-RBL2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity Purification |
| 【Gene ID】：5934 | 【Swiss Prot】：Q08999 |
| 【Tested applications】：IHC,WB,ELISA | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:30-150. ELISA 1:5000-10000. | |
| 【Immunogen】：A synthetic peptide of human RBL2 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Retinoblastoma-like protein 2 is a protein that in humans is encoded by the RBL2 gene. Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation.
Verified picture:
Western blot analysis with RBL2 antibody diluted at 1:200;Lane:Lncap
Immunohistochemistry of paraffin-embedded Human lung cancer using RBL2 antibody diluted at 1:40