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Anti-RASSF7 Polyclonal Antibody
Cat: K110416P
Summary:
【Product name】:Anti-RASSF7 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8045 【Swiss Prot】:Q02833
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:A synthetic peptide of human RASSF7
【Public Immunogen Range】:323-373/373aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
Verified picture:
Western blot analysis with RASSF7 antibody diluted at 1:2000;Lane:HepG2