Anti-RASSF7 Polyclonal Antibody - Biotin
Cat: K110416P - Biotin
Summary:
| 【Product name】：Anti-RASSF7 Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8045 | 【Swiss Prot】：Q02833 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human RASSF7 | |
| 【Public Immunogen Range】：323-373/373aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
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