Anti-CLN5 Polyclonal Antibody
Cat: K110424P
Summary:
| 【Product name】：Anti-CLN5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1203 | 【Swiss Prot】：O75503 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CLN5 | |
| 【Public Immunogen Range】：180-230/358aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).
Verified picture:
Immunohistochemistry of paraffin-embedded Human renal cancer using CLN5 antibody diluted at 1:100