Anti-MATR3 Polyclonal Antibody
Cat: K110464P
Summary:
| 【Product name】：Anti-MATR3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9782 | 【Swiss Prot】：P43243 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human MATR3 | |
| 【Public Immunogen Range】：140-190/847aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). May bind to specific miRNA hairpins (PubMed:28431233).
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer using MATR3 antibody diluted at 1:200
Western blot analysis with MATR3 antibody diluted at 1:2000;Lane:Mouse brain,Rat brain,HeLa,HEK293,NIH3T3,U251MG,SH-SY5Y,HepG2,Jurkat,293T,MCF7,K562,Mouse thymus