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Anti-NTAQ1 Polyclonal Antibody
Cat: K110487P
Summary:
【Product name】:Anti-NTAQ1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:55093 【Swiss Prot】:Q96HA8
【Tested applications】:WB,IHC,ELISA
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human NTAQ1
【Public Immunogen Range】:1-205aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
Verified picture:
Immunohistochemistry of paraffin-embedded Human thyroid cancer using NTAQ1 antibody diluted at 1:100
Immunohistochemistry of paraffin-embedded Human colorectal cancer using NTAQ1 antibody diluted at 1:100
Immunohistochemistry of paraffin-embedded Human prostate cancer using NTAQ1 antibody diluted at 1:100
Western blot analysis with NTAQ1 antibody diluted at 1:2000;Lane:A431