Anti-TGFBR2 Polyclonal Antibody
Cat: K110508P
Summary:
| 【Product name】：Anti-TGFBR2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7048 | 【Swiss Prot】：P37173 |
| 【Tested applications】：WB,IHC,IF | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:100-300. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TGFBR2 | |
| 【Public Immunogen Range】：1-166aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
TGF beta Receptor II (TGFBR2) is a member of the transforming growth factor-β (TGF-β) superfamily, which are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis (PMID: 10974075). TGFBR2 result in both SMAD4-dependent constraint of proliferation and SMAD4-independent activation of apoptosis (PMID: 29396446). It has some isoforms with the molecular weight of 70-80 kDa and ~90 kDa after glycosylated.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer using TGFBR2 antibody diluted at 1:200
Western blot analysis with TGFBR2 antibody diluted at 1:5000;Lane:Mouse lung