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Anti-POU2F1 Polyclonal Antibody
Cat: K110579P
Summary:
【Product name】:Anti-POU2F1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:5451 【Swiss Prot】:P14859
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:Recombinant protein of human POU2F1
【Public Immunogen Range】:1-350aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.(Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer using POU2F1 antibody diluted at 1:200