Anti-HSD3B7 Polyclonal Antibody - SAlexa Fluor 633
Cat: K110609P - SAlexa Fluor 633
Summary:
| 【Product name】：Anti-HSD3B7 Polyclonal Antibody - SAlexa Fluor 633 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：80270 | 【Swiss Prot】：Q9H2F3 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human HSD3B7 | |
| 【Public Immunogen Range】：1-282aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
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