Anti-FERMT3 Polyclonal Antibody
Cat: K110620P
Summary:
| 【Product name】：Anti-FERMT3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：83706 | 【Swiss Prot】：Q86UX7 |
| 【Tested applications】：WB,IHC,ELISA | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human FERMT3 | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Verified picture:
Western blot analysis with FERMT3 antibody diluted at 1:2000;Lane:K-562,THP-1,Jurkat
Immunohistochemistry of paraffin-embedded Human renal cancer using FERMT3 antibody diluted at 1:200