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Anti-CEBPB Polyclonal Antibody - SAlexa Fluor 405
Cat: K110634P - SAlexa Fluor 405
Summary:
【Product name】:Anti-CEBPB Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:1051 【Swiss Prot】:P17676
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:A synthetic peptide of human CEBPB
【Public Immunogen Range】:30-80/345aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:1741402, PubMed:9374525, PubMed:12048245, PubMed:18647749). Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipocytes but has an antiproliferative effect on T-cells by repressing MYC expression, facilitating differentiation along the T-helper 2 lineage. Binds to regulatory regions of several acute-phase and cytokines genes and plays a role in the regulation of acute-phase reaction and inflammation. Plays also a role in intracellular bacteria killing (By similarity). During adipogenesis, is rapidly expressed a
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