Anti-WASF1 Polyclonal Antibody
Cat: K110649P
Summary:
| 【Product name】：Anti-WASF1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8936 | 【Swiss Prot】：Q92558 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human WASF1 | |
| 【Public Immunogen Range】：225-275/559aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Verified picture:
Western blot analysis with WASF1 antibody diluted at 1:5000;Lane:Mouse brain,Rat brain
Immunohistochemistry of paraffin-embedded Human colorectal cancer using WASF1 antibody diluted at 1:100.