Anti-KCTD13 Polyclonal Antibody - SAlexa Fluor 488
Cat: K110701P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-KCTD13 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：253980 | 【Swiss Prot】：Q8WZ19 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human KCTD13 | |
| 【Public Immunogen Range】：10-60/329aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission (By similarity).
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