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Anti-USP12 Polyclonal Antibody - SAlexa Fluor 488
Cat: K110708P - SAlexa Fluor 488
Summary:
【Product name】:Anti-USP12 Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:219333 【Swiss Prot】:O75317
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human USP12
【Public Immunogen Range】:15-65/370aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035).
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