Anti-MAPK6 Polyclonal Antibody
Cat: K110758P
Summary:
| 【Product name】：Anti-MAPK6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：5597 | 【Swiss Prot】：Q16659 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human MAPK6 | |
| 【Public Immunogen Range】：373-722aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).
Verified picture:
Western blot analysis with MAPK6 antibody diluted at 1:2000;Lane:U-251,A549,A431,C2C12
Immunohistochemistry of paraffin-embedded Human breast cancer with MAPK6 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded Human colorectal cancer with MAPK6 antibody diluted at 1:200