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Anti-TPRKB Polyclonal Antibody - SAlexa Fluor 680
Cat: K110763P - SAlexa Fluor 680
Summary:
【Product name】:Anti-TPRKB Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:51002 【Swiss Prot】:Q9Y3C4
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:200-1000. IHC 1:100-300.
【Immunogen】:Recombinant protein of human TPRKB
【Public Immunogen Range】:1-175aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
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