Anti-UNG Polyclonal Antibody
Cat: K110791P
Summary:
| 【Product name】：Anti-UNG Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7374 | 【Swiss Prot】：P13051 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human UNG | |
| 【Public Immunogen Range】：185-235/313aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Verified picture:
Western blot analysis with UNG antibody diluted at 1:2000;Lane:Raji
Immunohistochemistry of paraffin-embedded Human renal cancer with UNG antibody diluted at 1:100