Anti-MFNG Polyclonal Antibody - Cy7
Cat: K110808P - Cy7
Summary:
| 【Product name】：Anti-MFNG Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4242 | 【Swiss Prot】：O00587 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human MFNG | |
| 【Public Immunogen Range】：271-321/321aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).
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