Anti-ARHGAP22 Polyclonal Antibody
Cat: K110820P
Summary:
| 【Product name】：Anti-ARHGAP22 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：58504 | 【Swiss Prot】：Q7Z5H3 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human ARHGAP22 | |
| 【Public Immunogen Range】：350-400/698aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).
Verified picture:
Western blot analysis with ARHGAP22 antibody diluted at 1:2000;Lane:Mouse lung
Immunohistochemistry of paraffin-embedded Human breast cancer with ARHGAP22 antibody diluted at 1:100