Anti-RACGAP1 Polyclonal Antibody
Cat: K110846P
Summary:
| 【Product name】：Anti-RACGAP1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：29127 | 【Swiss Prot】：Q9H0H5 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human RACGAP1 | |
| 【Public Immunogen Range】：185-235/632aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with RACGAP1 antibody diluted at 1:200.
Western blot analysis with RACGAP1 antibody diluted at 1:2000;Lane: COS7,A431,Jurkat,HEK293,293T,K-562.
Immunohistochemistry of paraffin-embedded Human stomach cancer with RACGAP1 antibody diluted at 1:200.