Anti-OPHN1 Polyclonal Antibody - SAlexa Fluor 594
Cat: K110968P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-OPHN1 Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4983 | 【Swiss Prot】：O60890 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human OPHN1 | |
| 【Public Immunogen Range】：1-312aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).
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