Anti-CD86（PE）Monoclonal Antibody - SAlexa Fluor 633
Cat: K009926M - SAlexa Fluor 633
Summary:
| 【Product name】：Anti-CD86（PE）Monoclonal Antibody - SAlexa Fluor 633 | 【Source】：Rat |
| 【Isotype】：IgG2a | 【Purification】：Affinity purification |
| 【Gene ID】：942 | 【Swiss Prot】：P42081 |
| 【Tested applications】：FCM | |
| 【Recommended dilution】：FCM:10^6cells加0.13ug | |
| 【Immunogen】：LPS-activated CBA/Ca mouse spleen B cells | |
| 【Storage】：Store at 2-8℃. Avoid exposure to light. | |
Background:
CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335)
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