Anti-Neuropilin 1 Monoclonal Antibody
Cat: K009929M
Summary:
| 【Product name】：Anti-Neuropilin 1 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Protein A purification |
| 【Gene ID】：8829 | 【Swiss Prot】：O14786 |
| 【Tested applications】：ELISA,IF,FCM,WB | |
| 【Recommended dilution】：WB 1:1000-6000. IF 1:50-500. | |
| 【Immunogen】：Recombinant protein of human Neuropilin 1 | |
| 【Public Immunogen Range】：1-300aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Neuropilin-1 (NRP1) is a a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
Verified picture:
Western blot analysis with Neuropilin 1 antibody diluted at 1:3000;Lane: Human placenta Pig brain.
Immunofluorescence analysis of SH-SY5Y cells using Neuropilin 1 antibody diluted at 1:100.