Anti-Phospho-RIPK1 (Ser161) Monoclonal Antibody - SAlexa Fluor 568
Cat: K009942M - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-Phospho-RIPK1 (Ser161) Monoclonal Antibody - SAlexa Fluor 568 | 【Source】：Mouse |
| 【Isotype】：IgG1 | 【Purification】：Protein G purification |
| 【Gene ID】：8737 | 【Swiss Prot】：Q13546 |
| 【Tested applications】：ELISA,IF,IHC,WB | |
| 【Recommended dilution】：WB 1:1000-5000. IHC 1:250-1000. IF 1:200-800. | |
| 【Immunogen】：A synthetic peptide of human RIPK1 (Phospho-Ser161) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis and necroptosis and belongs to a novel class of kinases thatfunction in cell survival and cell death mechanisms(PMID:22685397 ).It has 2 isoforms produced by alternative splicing.It also can exist as the protein with lower molecular weight about 25kd and 45kd in HAEC and HUVEC(PMID:22685397).
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