Anti-P38 MAPK Monoclonal Antibody
Cat: K009944M
Summary:
| 【Product name】：Anti-P38 MAPK Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG2b | 【Purification】：Protein A purification |
| 【Gene ID】：1432 | 【Swiss Prot】：Q16539 |
| 【Tested applications】：ELISA,IHC,WB | |
| 【Recommended dilution】：WB 1:2000-6000. IHC 1:250-1000. | |
| 【Immunogen】：Recombinant protein of human P38 MAPK. | |
| 【Public Immunogen Range】：1-307aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
Verified picture:
Western blot analysis with p38 MAPK antibody diluted at 1:5000;Lane: HeLa Jurkat HEK-293 HSC-T6 MCF-7.
Immunohistochemistry of paraffin-embedded human lung cancer with p38 MAPK antibody diluted at 1:500.