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Anti-P38 MAPK Monoclonal Antibody - SAlexa Fluor 680
Cat: K009944M - SAlexa Fluor 680
Summary:
【Product name】:Anti-P38 MAPK Monoclonal Antibody - SAlexa Fluor 680 【Source】:Mouse
【Isotype】:IgG2b 【Purification】:Protein A purification
【Gene ID】:1432 【Swiss Prot】:Q16539
【Tested applications】:ELISA,IHC,WB
【Recommended dilution】:WB 1:2000-6000. IHC 1:250-1000.
【Immunogen】:Recombinant protein of human P38 MAPK.
【Public Immunogen Range】:1-307aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
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