Anti-P38 MAPK Monoclonal Antibody - SAlexa Fluor 555
Cat: K009944M - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-P38 MAPK Monoclonal Antibody - SAlexa Fluor 555 | 【Source】：Mouse |
| 【Isotype】：IgG2b | 【Purification】：Protein A purification |
| 【Gene ID】：1432 | 【Swiss Prot】：Q16539 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human P38 MAPK. | |
| 【Public Immunogen Range】：1-307aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.
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