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Anti-SLC25A11 Polyclonal Antibody - SAlexa Fluor 532
Cat: K111043P - SAlexa Fluor 532
Summary:
【Product name】:Anti-SLC25A11 Polyclonal Antibody - SAlexa Fluor 532 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:8402 【Swiss Prot】:Q02978
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human SLC25A11
【Public Immunogen Range】:145-195/314aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (PubMed:21448454). Involved in the regulation of apoptosis (By similarity). Acts as a tumor-suppressor gene implicated in the predisposition to metastatic paraganglioma.
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