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Anti-MYBL1 Polyclonal Antibody - SAlexa Fluor 680
Cat: K111078P - SAlexa Fluor 680
Summary:
【Product name】:Anti-MYBL1 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:4603 【Swiss Prot】:P10243
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:A synthetic peptide of human MYBL1
【Public Immunogen Range】:525-575/752aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:8058310, PubMed:7987850). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism (By similarity). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (By similarity). Transcriptional activator of SOX30 (By similarity).
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