Anti-PDE10A Polyclonal Antibody
Cat: K111109P
Summary:
| 【Product name】：Anti-PDE10A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10846 | 【Swiss Prot】：Q9Y233 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human PDE10A | |
| 【Public Immunogen Range】：20-70/779aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.
Verified picture:
Western blot analysis with PDE10A antibody diluted at 1:2000;Lane: Rat brain.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PDE10A antibody diluted at 1:200.