Anti-ITGA5 (heavy chain,Cleaved-Phe42) Polyclonal Antibody - Biotin
Cat: K111133P - Biotin
Summary:
| 【Product name】：Anti-ITGA5 (heavy chain,Cleaved-Phe42) Polyclonal Antibody - Biotin | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3678 | 【Swiss Prot】：P08648 |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human ITGA5 (heavy chain,Cleaved-Phe42) | |
| 【Public Immunogen Range】：30-80/1049aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
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