Anti-SEMA4C Polyclonal Antibody
Cat: K111135P
Summary:
| 【Product name】：Anti-SEMA4C Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：54910 | 【Swiss Prot】：Q9C0C4 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human SEMA4C | |
| 【Public Immunogen Range】：320-370/833aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with SEMA4C antibody diluted at 1:200.