Anti-TGFBR3 Polyclonal Antibody
Cat: K111137P
Summary:
| 【Product name】：Anti-TGFBR3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7049 | 【Swiss Prot】：Q03167 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human TGFBR3 | |
| 【Public Immunogen Range】：545-595/851aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human endometrial cancer with TGFBR3 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human renal cancer with TGFBR3 antibody diluted at 1:100.