Anti-LONP2 Polyclonal Antibody - SAlexa Fluor 750
Cat: K111143P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-LONP2 Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：83752 | 【Swiss Prot】：Q86WA8 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human LONP2 | |
| 【Public Immunogen Range】：455-505/852aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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