Anti-LONP2 Polyclonal Antibody - Cy5
Cat: K111143P - Cy5
Summary:
| 【Product name】：Anti-LONP2 Polyclonal Antibody - Cy5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：83752 | 【Swiss Prot】：Q86WA8 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human LONP2 | |
| 【Public Immunogen Range】：455-505/852aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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