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Anti-PRKD2 Polyclonal Antibody
Cat: K111154P
Summary:
【Product name】:Anti-PRKD2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:25865 【Swiss Prot】:Q9BZL6
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human PRKD2
【Public Immunogen Range】:815-865/878aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PRKD2 antibody diluted at 1:100.