Anti-ING2 Polyclonal Antibody - SAlexa Fluor 350
Cat: K111246P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-ING2 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3622 | 【Swiss Prot】：Q9H160 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human ING2 | |
| 【Public Immunogen Range】：1-281aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
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